Timing metformin to avoid negative effects on exercise adaptation: plausibility | Rhonda Patrick
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To circumvent metformin's blunting effect on exercise-derived benefits, some researchers have suggested administering the drug on days when exercise is not performed. However, this may not be a straight forward solution due to the many factors involved. In this clip, Dr. Rhonda Patrick discusses whether timing metformin administration apart from exercise may be a strategy to overcome some of its adverse effects.
Important for the endocrine enhancing properties of exercise. Exerkines are exercise-induced hormonal-like factors which mediate the systemic benefits of exercise through autocrine, paracrine, and/or endocrine properties.[1]
- ^ Helge, Jørn Wulff; Moritz, Thomas; Morville, Thomas; Clemmensen, Christoffer; Dela, Flemming (2020). Plasma Metabolome Profiling Of Resistance Exercise And Endurance Exercise In Humans Cell Reports 33, 13.
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