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A wide variety of lifestyle factors, including exercise and nutrition, have well-established influences on healthspan and lifespan. The search for molecules that mimic the effects of exercise and caloric restriction is an active field of investigation. While exercise and caloric restriction have the potential to slow aging, rejuvenation has the potential to repair the damages associated with aging once they have occurred. In this clip, Dr. Eric Verdin explains how exercise and nutrition form the cornerstone of strategies to slow aging, but exciting approaches lie ahead.
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The practice of long-term restriction of dietary intake, typically characterized by a 20 to 50 percent reduction in energy intake below habitual levels. Caloric restriction has been shown to extend lifespan and delay the onset of age-related chronic diseases in a variety of species, including rats, mice, fish, flies, worms, and yeast.
The years of a person’s life spent free of disease.
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