Episodes

Can exercise replace alcohol cravings?

Posted on November 2nd 2022 (about 1 month)

When people exercise as part of a treatment for alcohol abuse disorder it reduces their volume of alcohol consumption. But why? One reason may be FGF21.

Dr. George Church: Rewriting Genomes to Eradicate Disease and Aging

Posted on August 23rd 2022 (3 months)

In this episode, George Church, Ph.D., one of the world's leading geneticists, discusses his work on how revolutionary technologies such as multiplex genome editing and genome writing could advance human health.

Is there a limit to human longevity?

Posted on July 20th 2022 (5 months)

Lifestyle factors and new technologies offer the promise of living longer, healthier lives, but is there a limit to the human lifespan? This episode explores the different theories supporting this hotly debated topic.

Stuart Phillips, PhD, on Building Muscle with Resistance Exercise and Reassessing Protein Intake

Posted on June 29th 2022 (5 months)

In this episode, Dr. Stuart Phillips discusses the roles exercise and nutrition play in influencing human skeletal muscle protein turnover and highlights the importance of maintaining muscle mass and strength throughout the lifespan.

Intestinal Permeability: the Bacterial link to Aging, Brain Barrier Dysfunction & Metabolic Disorder

Posted on May 30th 2022 (6 months)

In this keynote address, Dr. Rhonda Patrick describes how the loss of health and integrity of the intestinal barrier influences multiple aspects of human health – including cardiometabolic function, neurological health, behavior, and more.

Dr. Dominic D'Agostino on Developing a Well-Designed Ketogenic Diet and Harnessing its Benefits

Posted on April 28th 2022 (7 months)

In this episode, Dr. Dominic D'Agostino, a world-class researcher and ketogenic diet practitioner, discusses how ketones affect exercise performance, reduce inflammation, and improve neurological health.

Sauna Benefits Deep Dive and Optimal Use with Dr. Rhonda Patrick & MedCram

Posted on April 13th 2022 (8 months)

This episode features a discussion with MedCram co-founder Kyle Allred about all things sauna. From sauna's use as an exercise mimetic to its anti-inflammatory, mood-elevating, and detoxifying properties.

Morgan Levine, PhD, on PhenoAge and the Epigenetics of Age Acceleration: Can We Change the Pace?

Posted on April 11th 2022 (8 months)

Morgan Levine, Ph.D., is a founding principal investigator at Altos Labs and an assistant professor of pathology at the Yale University School of Medicine.

Cold-Water Immersion and Cryotherapy: Neuroendocrine and Fat Browning Effects

Posted on April 1st 2022 (8 months)

In response to cold-water immersion, the body increases circulation of norepinephrine. This physiological response sets off a cascade of adaptive effects that affect metabolism, the brain, and genetic expression.

Peter Diamandis, MD, and Tony Robbins: Strategies that promote longevity now – and in the very near future

Posted on March 9th 2022 (9 months)

Peter Diamandis, MD and Tony Robbins are entrepreneurs and authors of "Life Force," a book on precision medicine and health technology.

Dr. Eran Elinav: Microbiome Insights into Personalized Response to Diet, Obesity, and Leaky Gut

Posted on February 8th 2022 (10 months)

The work on Eran Elinav, MD, PhD focuses on understanding the complex interactions between humans and the bacteria that reside in their gut and how these interactions shape human health and disease.

Can Psilocybin Treat Depression?

Posted on December 28th 2021 (11 months)

Research suggests psilocybin may have effects therapeutic for depression. In this episode, we discuss some of the qualities of the psychedelic experience that most lend psilocybin to be potentially therapeutically beneficial for depression.

Dr. Bill Harris on the Omega-3 Index, Increasing Omega-3 to Improve Longevity & Heart Disease Risk

Posted on December 7th 2021 (12 months)

Dr. Bill Harris is one of the world's preeminent experts in the field of omega-3 fatty acid research. His work focuses on the roles that fatty acids play in cardiovascular and neurocognitive health.

Dr. Ashley Mason on Sauna Use for Depression, Conquering Insomnia, and Mindfully Breaking Bad Habits

Posted on November 2nd 2021 (about 1 year)

Dr. Ashley Mason is a clinical psychologist whose research focuses on sauna use for depression and director of the Sleep, Eating, and Affect Laboratory at the Osher Center for Integrative Medicine at UCSF.

Dr. Mark Mattson on the Benefits of Stress, Metabolic Switching, Fasting, and Hormesis

Posted on October 6th 2021 (about 1 year)

In this episode, Dr. Mark Mattson discusses how stress is beneficial – even essential – to human survival, and how exercise and intermittent fasting induce stress to promote health.

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