Episodes

Dr. Steve Horvath on epigenetic aging to predict healthspan: the DNA PhenoAge and GrimAge clocks

Posted on December 18th 2020 (over 2 years)

Consistent patterns of age-based alterations in DNA methylation can be harnessed to estimate age, serving as a sort of "clock," the premise of which is truly remarkable: Predict a person's age (or even lifespan), based on chemical modifications to their DNA...

Q&A #17 with Dr. Jed Fahey + Rhonda on Sulforaphane and Moringa

Posted on November 16th 2020 (over 2 years)

A special two-hour Q&A with Dr. Jed Fahey, an expert of chemoprotection and phytochemicals.

Dr. Giselle Petzinger on Exercise for Parkinson's Disease

Posted on October 13th 2020 (over 2 years)

In this episode, Dr. Giselle Petzinger discusses exciting findings in Parkinson's disease research, with an emphasis on exercise's role in neuroplasticity and delaying disease progression.

Dr. David Sinclair on Informational Theory of Aging, Nicotinamide Mononucleotide, Resveratrol & More

Posted on November 6th 2019 (over 3 years)

David Sinclair, PhD, is a professor in the Department of Genetics at Harvard Medical School and co-director of the Paul F. Glenn Center for the Biological Mechanisms of Aging. His work focuses on understanding the mechanisms that drive human aging and ident...

Dr. Elissa Epel on Telomeres and the Role of Stress Biology in Cellular Aging

Posted on June 10th 2019 (almost 4 years)

Elissa Epel, PhD, is a Professor in the Department of Psychiatry at the University of California, San Francisco where she serves as the director of the Aging, Metabolism, and Emotions Center. Her research centers on the mechanisms of healthy aging and the a...

Dr. Matthew Walker on Sleep for Enhancing Learning, Creativity, Immunity, and Glymphatic System

Posted on February 28th 2019 (about 4 years)

Matthew Walker, Ph.D., is a professor of neuroscience and psychology at the University of California, Berkeley, and serves as the Director of the Center for Human Sleep Science. Formerly, Dr. Walker served as a professor of psychiatry at the Harvard Medical...

Fasting Q&A with Dr. Rhonda Patrick and Mike Maser

Posted on January 17th 2019 (over 4 years)

This episode features a Q&A session on fasting-related topics with Dr. Rhonda Patrick and Mike Maser of Zero Fasting Tracker.

Dr. Dale Bredesen on Preventing and Reversing Alzheimer's Disease

Posted on October 1st 2018 (over 4 years)

Dr. Bredesen’s is known for his work in translating his scientific research into effective treatments for Alzheimer’s disease. He is the author of the book The End of Alzheimer's and the ReCODE protocol – reversal of cognitive decline – a protocol that offe...

Dr. Valter Longo on Resetting Autoimmunity and Rejuvenating Systems with Prolonged Fasting & the FMD

Posted on July 9th 2018 (almost 5 years)

Round 2 with Dr. Valter Longo. Valter Longo, PhD, is a biochemist and professor of gerontology and biological sciences at the University of Southern California (USC). He directs the USC Longevity Institute as well as the Oncology and Longevity Program at th...

Dr. Charles Raison on Depression, the Immune-Brain Interface & Whole-Body Hyperthermia

Posted on March 19th 2018 (about 5 years)

Dr. Charles Raison’s research focuses on inflammation and the development of depression in response to illness and stress. He also examines the physical and behavioral effects of compassion training on the brain, inflammatory processes, and behavior as well...

Dr. Eric Verdin on Ketogenic Diet, Longevity, Beta-Hydroxybutyrate, HDAC Inhibitors, & NAD+

Posted on December 13th 2017 (over 5 years)

Eric M. Verdin, M.D. is the fifth president and chief executive officer of the Buck Institute for Research on Aging and is a professor of Medicine at UCSF.

Dr. Satchin Panda on Practical Implementation of Time-Restricted Eating & Shift Work Strategies

Posted on October 30th 2017 (over 5 years)

It's time to abandon ad libitum! This is an almost two-hour round 2 episode with Dr. Satchin Panda focused on practical implementation of time-restricted eating, various circadian insights, and much more.

Dr. Guido Kroemer on Autophagy, Caloric Restriction Mimetics, Fasting & Protein Acetylation

Posted on July 31st 2017 (almost 6 years)

Dr. Guido Kroemer is a professor at the University of Paris Descartes and an expert in immunology, cancer biology, aging, and autophagy.

Dr. Jari Laukkanen on Sauna Use for the Prevention of Cardiovascular & Alzheimer’s Disease

Posted on June 15th 2017 (almost 6 years)

Dr. Laukkanen has been conducting long-term trials looking at the health effects of sauna use in a population of over 2,000 middle-aged men in Finland. The results? Massive reductions in mortality and memory disease in a dose-dependent fashion at 20-year fo...

Judith Campisi, Ph.D., on Cellular Senescence, Mitochondrial Dysfunction, Cancer & Aging

Posted on April 28th 2017 (about 6 years)

Dr. Judith Campisi is a professor of biogerontology at the Buck Institute for Research on Aging, a co-editor in chief of the _Aging Journal_ and an expert on the role of cellular senescence in the aging process and development of cancer.

Want to view all episodes on a single page?
View our episode archive.