Episode archive

Posted on February 27th 2023 (3 months)

Dr. Axel Montagne studies how, when, and where the blood-brain barrier becomes dysfunctional preceding dementia and in the earliest stages of age-related cognitive decline.

Posted on December 6th 2022 (6 months)

Dr. Brad Schoenfeld is a professor at Lehman College, CUNY, in the Bronx, New York.

Posted on August 23rd 2022 (10 months)

In this episode, George Church, Ph.D., one of the world's leading geneticists, discusses his work on how revolutionary technologies such as multiplex genome editing and genome writing could advance human health.

Posted on June 29th 2022 (11 months)

In this episode, Dr. Stuart Phillips discusses the roles exercise and nutrition play in influencing human skeletal muscle protein turnover and highlights the importance of maintaining muscle mass and strength throughout the lifespan.

Posted on April 28th 2022 (about 1 year)

In this episode, Dr. Dominic D'Agostino, a world-class researcher and ketogenic diet practitioner, discusses how ketones affect exercise performance, reduce inflammation, and improve neurological health.

Posted on April 11th 2022 (about 1 year)

Morgan Levine, Ph.D., is a founding principal investigator at Altos Labs and an assistant professor of pathology at the Yale University School of Medicine.

Posted on March 9th 2022 (about 1 year)

Peter Diamandis, MD and Tony Robbins are entrepreneurs and authors of "Life Force," a book on precision medicine and health technology.

Posted on February 8th 2022 (over 1 year)

The work on Eran Elinav, MD, PhD focuses on understanding the complex interactions between humans and the bacteria that reside in their gut and how these interactions shape human health and disease.

Posted on December 7th 2021 (over 1 year)

Dr. Bill Harris is one of the world's preeminent experts in the field of omega-3 fatty acid research. His work focuses on the roles that fatty acids play in cardiovascular and neurocognitive health.

Posted on November 2nd 2021 (over 1 year)

Dr. Ashley Mason is a clinical psychologist whose research focuses on sauna use for depression and director of the Sleep, Eating, and Affect Laboratory at the Osher Center for Integrative Medicine at UCSF.

Posted on October 6th 2021 (over 1 year)

In this episode, Dr. Mark Mattson discusses how stress is beneficial – even essential – to human survival, and how exercise and intermittent fasting induce stress to promote health.

Posted on September 27th 2021 (over 1 year)

This is a special episode bringing you up-to-date science on COVID-19 vaccination featuring a conversation between Dr. Rhonda Patrick and MedCram founders Dr. Roger Seheult and physician assistant Kyle Allred.

Posted on June 15th 2021 (almost 2 years)

The work of Dr. Satchidananda Panda and his lab focuses on chronobiology, the study of the day-night cycles that drive the multifaceted activities of the human body, using genetic, genomic, and biochemical approaches.

Posted on May 24th 2021 (about 2 years)

Dr. Michael Snyder discusses the future of personalized medicine through the use of technology like continuous glucose monitor "big data" smart analytical techniques.

Posted on February 3rd 2021 (over 2 years)

Dr. Roger Seheult is the co-founder of MedCram Videos, a frontline pulmonologist, and quadruple board-certified physician whose COVID-19 insights have garnered millions of views on YouTube.

Posted on December 18th 2020 (over 2 years)

Consistent patterns of age-based alterations in DNA methylation can be harnessed to estimate age, serving as a sort of "clock," the premise of which is truly remarkable: Predict a person's age (or even lifespan), based on chemical modifications to their DNA that reflect the biological life history of the organism. Dr. Steve Horvath has analyzed large data sets of DNA methylation profiles to derive an algorithm that accurately predicts a person's chronological age across multiple cells, tissues, and organs, and even mammalian species. He built on this algorithm to develop second-generation clocks that could predict time-to-death among people of the same chronological age, as well as lifespan and healthspan. In this episode, Dr. Steven Horvath describes epigenetic clocks and their role in predicting – and possibly slowing – aging.

Posted on November 16th 2020 (over 2 years)

A special two-hour Q&A with Dr. Jed Fahey, an expert of chemoprotection and phytochemicals.

Posted on October 13th 2020 (over 2 years)

In this episode, Dr. Giselle Petzinger discusses exciting findings in Parkinson's disease research, with an emphasis on exercise's role in neuroplasticity and delaying disease progression.

Posted on November 6th 2019 (over 3 years)

David Sinclair, PhD, is a professor in the Department of Genetics at Harvard Medical School and co-director of the Paul F. Glenn Center for the Biological Mechanisms of Aging. His work focuses on understanding the mechanisms that drive human aging and identifying ways to slow or reverse aging's effects.

Posted on June 10th 2019 (almost 4 years)

Elissa Epel, PhD, is a Professor in the Department of Psychiatry at the University of California, San Francisco where she serves as the director of the Aging, Metabolism, and Emotions Center. Her research centers on the mechanisms of healthy aging and the associations between stress, telomere length, addiction, eating, and metabolic health.

Posted on February 28th 2019 (over 4 years)

Matthew Walker, Ph.D., is a professor of neuroscience and psychology at the University of California, Berkeley, and serves as the Director of the Center for Human Sleep Science. Formerly, Dr. Walker served as a professor of psychiatry at the Harvard Medical School. He is the author of the New York Times best-selling book _Why We Sleep: Unlocking the Power of Sleep and Dreams_.

Posted on January 17th 2019 (over 4 years)

This episode features a Q&A session on fasting-related topics with Dr. Rhonda Patrick and Mike Maser of Zero Fasting Tracker.

Posted on October 1st 2018 (over 4 years)

Dr. Bredesen’s is known for his work in translating his scientific research into effective treatments for Alzheimer’s disease. He is the author of the book The End of Alzheimer's and the ReCODE protocol – reversal of cognitive decline – a protocol that offers a new approach to treatment that has reversed symptoms in patients with mild cognitive impairment and Alzheimer’s disease.

Posted on July 9th 2018 (almost 5 years)

Round 2 with Dr. Valter Longo. Valter Longo, PhD, is a biochemist and professor of gerontology and biological sciences at the University of Southern California (USC). He directs the USC Longevity Institute as well as the Oncology and Longevity Program at the Institute of Molecular Oncology Foundation in Milan, Italy.

Posted on March 19th 2018 (about 5 years)

Dr. Charles Raison’s research focuses on inflammation and the development of depression in response to illness and stress. He also examines the physical and behavioral effects of compassion training on the brain, inflammatory processes, and behavior as well as the effect of heat stress as a potentially therapeutic intervention major depressive disorder.

Posted on December 13th 2017 (over 5 years)

Eric M. Verdin, M.D. is the fifth president and chief executive officer of the Buck Institute for Research on Aging and is a professor of Medicine at UCSF.

Posted on October 30th 2017 (over 5 years)

It's time to abandon ad libitum! This is an almost two-hour round 2 episode with Dr. Satchin Panda focused on practical implementation of time-restricted eating, various circadian insights, and much more.

Posted on July 31st 2017 (almost 6 years)

Dr. Guido Kroemer is a professor at the University of Paris Descartes and an expert in immunology, cancer biology, aging, and autophagy.

Posted on June 15th 2017 (almost 6 years)

Dr. Laukkanen has been conducting long-term trials looking at the health effects of sauna use in a population of over 2,000 middle-aged men in Finland. The results? Massive reductions in mortality and memory disease in a dose-dependent fashion at 20-year follow-up.

Posted on April 28th 2017 (about 6 years)

Dr. Judith Campisi is a professor of biogerontology at the Buck Institute for Research on Aging, a co-editor in chief of the _Aging Journal_ and an expert on the role of cellular senescence in the aging process and development of cancer.

Posted on April 7th 2017 (about 6 years)

Dr. Gordon Lithgow is a professor of gerontology at the Buck Institute for Research on Aging. The topic of conversation in this episode is especially focused on Dr. Lithgow's work with C. elegans, which a tiny nematode worm he uses to interrogate questions involving the aging process and lifespan extension.

Posted on January 19th 2017 (over 6 years)

Dr. Jed W. Fahey is a nutritional biochemist with deep experience researching isothiocyanates like sulforaphane.

Posted on January 19th 2017 (over 6 years)

Dr. Roland Griffiths is a clinical pharmacologist at Johns Hopkins and one of the world's foremost researchers on the psychedelic compound psilocybin.

Posted on October 4th 2016 (over 6 years)

Dr. Rhonda Patrick speaks with Dr. Valter Longo, a professor of gerontology and biological sciences and director of the longevity institute at the University of Southern California.

Posted on July 8th 2016 (almost 7 years)

This episode features Dr. Ruth Patterson, a professor in the UC San Diego Department of Family Medicine and Public Health as well as Associate Director of Population Sciences and leader of the Cancer Prevention program at Moores Cancer Center at UC San Diego Health.

Posted on July 1st 2016 (almost 7 years)

Dr. Rhonda Patrick speaks with Dr. Satchin Panda, a professor at the Salk Institute for Biological Studies in La Jolla California. Satchin's work deals specifically with the timing of food and it's relationship with our biological clocks, which are governed by a circadian rhythm.

Posted on May 4th 2016 (about 7 years)

Dr. Rhonda Patrick speaks with Ray Cronise, a former NASA material scientist and co-founder of zero gravity, a company that offers weightless parabolic flights to consumers and researchers.

Posted on April 10th 2016 (about 7 years)

This podcast is with Dr. Dominic D'Agostino, an assistant professor at the University of South Florida in Tampa and all around expert on ketosis.

Posted on March 14th 2016 (about 7 years)

Dr. Peter Attia is the founder of Attia Medical, a medical practice with offices in San Diego and New York City, focusing on the applied science of longevity and optimal performance.

Posted on January 24th 2016 (over 7 years)

This podcast features Rich Roll. Rich is an author, a podcaster, as well as founder and first person to complete the EPIC5 Challenge.

Posted on January 3rd 2016 (over 7 years)

Dr. Darya Rose & husband Kevin Rose join Rhonda for a chat about multi-day silent meditation retreats, Kevin's experiments with a ketogenic diet, and some ideas and other projects he's working.

Posted on January 3rd 2016 (over 7 years)

Dr. Rhonda Patrick interviews Dr. Pierre Capel, professor emeritus in experimental immunology at the Utrecht University in the Netherlands where he researched a wide range of topics from genetic modification to cancer immunotherapy.

Posted on January 3rd 2016 (over 7 years)

Dr. Rhonda Patrick interviews Wim Hof and discusses the 2014 study on his technique with him.

Posted on January 3rd 2016 (over 7 years)

Ronald Krauss, M.D., is the director of atherosclerosis research at Children’s Hospital Oakland Research Institute and an adjunct professor at UCSF and UC Berkeley.

Posted on August 13th 2015 (almost 8 years)

Dr. Aubrey de Grey is a biomedical gerontologist and the founder of the SENS research foundation which aims to find technologies that can repair the various types of damage that occur during the aging process.

Posted on July 21st 2015 (almost 8 years)

Tim Ferriss, notorious self-experimenter, angel investor, startup advisor, NY Times bestselling author (3x), and much more.

Posted on July 4th 2015 (almost 8 years)

Dr. Rhonda Patrick speaks with Dr. Bruce Ames, about a micronutrient- and fiber-dense nutrition bar (referred to as the CHORI bar) that was developed in the Ames laboratory.

Posted on July 4th 2015 (almost 8 years)

Jim Kean is the CEO of National Pro Grid League (NPGL) and founder of WellnessFX.

Posted on February 12th 2015 (over 8 years)

Dr. Bruce Ames discusses his triage theory, which he proposes that the body has developed a rationing response to shortages of micronutrients (vitamins and minerals) throughout evolution.

Posted on December 17th 2014 (over 8 years)

Dr. Frans Kuypers and his lab pioneered a technique that helps retrieve pluripotent stem cells from placental tissue, which is routinely needless discarded worldwide.

Posted on December 3rd 2014 (over 8 years)

Contrary to commonly held beliefs, lactate is not the cause of muscle fatigue. Rather, it's an essential source of energy itself, greedily metabolized with a greater degree of preference than many other sources of energy, including glucose. Recent research suggests that the lactate metabolic pathway plays a critical role in the context of recovery from traumatic brain injury.

Posted on July 22nd 2014 (almost 9 years)

Dr. Terry Wahls discusses the protocol she used to reverse her secondary-progressive multiple sclerosis.