Aliquot #27: Health consequences of sleep deprivation, part I: Metabolic & immune health
Aliquot #27: Health consequences of sleep deprivation, part I: Metabolic & immune health
Poor sleep reduces the body's insulin sensitivity and changes a person's appetite, increasing the preference for high carbohydrate foods like pizza, pasta, and sweets. Lack of sleep also alters the gut microbiota and impairs immunity, putting us at risk for developing acute illnesses like colds and flu. Eventually, chronic poor sleep increases our risk for much more serious threats, such as cancer, unless we take steps to sleep better. This episode of the Aliquot feature Drs. Matthew Walker, David Sinclair, and Rhonda Patrick (in a members' Q&A).
Get these episodes in a convenient podcast format.
Aliquot episodes make great companion listening for a long drive. You can find these special members-only episodes alongside live recorded Q&As on The Aliquot, our official premium FoundMyFitness podcast.
Poor sleep reduces the body's insulin sensitivity and changes a person's appetite, increasing the preference for high carbohydrate foods like pizza, pasta, and sweets. Lack of sleep also alters the gut microbiota and impairs immunity, putting us at risk for developing acute illnesses like colds and flu. Eventually, chronic poor sleep increases our risk for much more serious threats, such as cancer, unless we take steps to sleep better. This episode of the Aliquot feature Drs. Matthew Walker, David Sinclair, and Rhonda Patrick (in a members' Q&A).
-
Introduction
-
Poor sleep affects the release of appetite-regulating hormones leptin and ghrelin (Matthew Walker discussion)
-
Fragmented sleep consistently led to higher fasting and postprandial blood glucose levels (David Sinclair discussion)
-
People who average less than seven hours of sleep are more likely to develop diabetes (Matthew Walker discussion)
Get email updates with the latest curated healthspan research
Support our work

Every other week premium members receive a special edition newsletter that summarizes all of the latest healthspan research.
Recent Aliquot Episodes

Aliquot #127: The Promise and Peril of Stimulants for Focus
In this Aliquot, Dr. Andrew Huberman, Brady Holmer, and I explore the science behind cognitive enhancers and how HIIT boosts...

Aliquot #126: The Science of Calcium for Bone Health and Beyond
In this Aliquot, I'll summarize the latest research on calcium absorption, supplementation, and dietary sources, exploring...

Aliquot #125: Why Screens Make Us Sick
In this Aliquot, Dr. Andrew Huberman and I explore the complexities of digital engagement, share strategies for managing...

Aliquot #124: How much sodium do you actually need?
In this Aliquot, I explore how genetics, lifestyle, and potassium balance influence sodium's role in...

Aliquot #123: Diet & Lifestyle Strategies for Optimizing Eye Health
In this Aliquot, you'll hear expert insights from Drs. Bruce Ames, Andrew Huberman, Axel Montagne, and me...