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I also want to add that while vitamin C is considered an antioxidant it does not act the same as other antioxidants such as vitamin E and NAC, which have actually been shown to accelerate tumor growth. Vitamin E and NAC can sequester reactive oxygen species (which activates cancer cell death) and prevents cancer cells from dying. Vitamin C does not act the same way. This is why it is VERY important to understand mechanisms and not make generalizations. Vitamin C is in constant homeostasis between oxidized and reduced forms and this depends on many factors including dose. When administered intravenously, the vitamin C dose is so high that it forms the oxidized form and this does a couple of important things that can kill cancer cells. First, it causes oxidative stress in cancer cells (a well known mechanism to activate cell death of a cancer cell). Second, it inhibits the glycolysis pathway, thus starving cancer cells of glucose.

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    I’d love to hear your comments on the following study on antioxidant risk in cancer that was recently published in PNAS. It’s an animal trial from Hong Kong which claims that antioxidant supplements including vitamin C may facilitate tumor growth, even though the research has only found that antioxidants produced inside the body may lead to such an effect.


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      Is there an article out there that explains all this oxidation business? It is talked about constantly but I don’t understand it very well.