I do a bit of MMA and have no noticeable deficits. Occasionally, I take some earth-shattering hits.
Understanding, that this is not medical advice, what could a person-who takes a really hard hit (one or two slip through) maybe once a month and isn’t on any medications-do?
How many milligrams of Tumeric w/piperin would a diligent reader of pub-med and other refereed literature take?
In some of the mouse studies for traumatic brain injury, mice were given 300 mg per kg of body weight following a traumatic event and this significantly reduced damage. This was given orally without piperine and is an astronomical amount (24 grams!) if translated to a 180 lb. male. )http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911034/) Theoretically, the piperine should make the curcuminoids 15-20-fold more bioavailable. 1g per day is what I take prophylactically, but if I were to have brain trauma I would probably up it to 5 grams after trauma.
5mg of piperine is enough to slow the metabolism of the curcuminoids in the bloodstream. Also, 3 grams of DHA per day for 30 days has been shown to reduce severity of brain trauma (http://www.ncbi.nlm.nih.gov/pubmed/21135750). The human brain (in a non-injured state) only takes up 4 mg/day of DHA and takes up much more EPA. From my research, it is important to have 2 grams of EPA and 1 gram of DHA per day. I’m doing a video on this really soon. In the case where TBI has occurred, brain can take up more DHA.
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I do a bit of MMA and have no noticeable deficits. Occasionally, I take some earth-shattering hits. Understanding, that this is not medical advice, what could a person-who takes a really hard hit (one or two slip through) maybe once a month and isn’t on any medications-do? How many milligrams of Tumeric w/piperin would a diligent reader of pub-med and other refereed literature take?
In some of the mouse studies for traumatic brain injury, mice were given 300 mg per kg of body weight following a traumatic event and this significantly reduced damage. This was given orally without piperine and is an astronomical amount (24 grams!) if translated to a 180 lb. male. )http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911034/) Theoretically, the piperine should make the curcuminoids 15-20-fold more bioavailable. 1g per day is what I take prophylactically, but if I were to have brain trauma I would probably up it to 5 grams after trauma. 5mg of piperine is enough to slow the metabolism of the curcuminoids in the bloodstream. Also, 3 grams of DHA per day for 30 days has been shown to reduce severity of brain trauma (http://www.ncbi.nlm.nih.gov/pubmed/21135750). The human brain (in a non-injured state) only takes up 4 mg/day of DHA and takes up much more EPA. From my research, it is important to have 2 grams of EPA and 1 gram of DHA per day. I’m doing a video on this really soon. In the case where TBI has occurred, brain can take up more DHA.