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Comments by PokeYouInDaEye
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    @foundmyfitness - How does this supplement formula compare to the Ames (triage) formula?

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      Would love to compare the Lemon formula with the Ames formula… @rhonda, is the Ames formula published anywhere?

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        Conclusion Based on clinical studies, creatine supplementation, particularly when combined with training, may potentially affect glucose uptake. In addition, creatine can maximize exercise capacity on GLUT and AMPK, improving insulin sensitivity. However, there are a very limited number of clinical interventions testing the effects of creatine supplementation in glucose metabolism precluding the prescription of this dietary supplement as part of the treatment of conditions characterized by insulin resistance. Regarding animal studies, the results were largely divergent confirming that species-specific responses do exist in relation to creatine studies. Given the potential of this intervention as an antiglycemic agent, evidenced by (scant) experimental and clinical data, further studies are needed to better understand the effects and underlying mechanism of creatine supplementation in modulating glycemia.

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          Aldehydes: Across brands, EC released 1/50th of the level of formaldehyde released by cigarettes. The highest level detected was six times lower than the level in cigarette smoke [138]

          Study on vape-mice lungs: The mice model has little relevance for estimating human risk and it does not raise any new safety concerns.

          Second-hand vape: the only study concerning this, the authors initially expressed concern, then asked the media to retract that statement.

          Summary of findings Two recent worldwide media headlines asserted that EC use is dangerous. These were based on misinterpreted research findings. A high level of formaldehyde was found when e-liquid was over-heated to levels unpalatable to EC users, but there is no indication that EC users are exposed to dangerous levels of aldehydes; stressed mice poisoned with very high levels of nicotine twice daily for two weeks were more likely to lose weight and die when exposed to bacteria and viruses, but this has no relevance for human EC users. The ongoing negative media campaigns are a plausible explanation for the change in the perception of EC safety (see Chapter 8). None of the studies reviewed above alter the conclusion of Professor Britton’s 2014 review for PHE. While vaping may not be 100% safe, most of the chemicals causing smoking-related disease are absent and the chemicals that are present pose limited danger. It had previously been estimated that EC are around 95% safer than smoking [10, 146]. This appears to remain a reasonable estimate.

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            “It turns out that aspirin not only increases the function of mitochondria, it also increases the number of mitochondria. Using a staining method called MitoTracker Green dye, the researchers discovered that aspirin increased the total concentration of mitochondria by two to three times. Since the most notable hallmark of aging is decreased numbers of mitochondria with decreased mitochondrial function, this data makes aspirin look like the best anti-aging substance that has ever come along.

            So should we all run out and start taking aspirin every day? I think there is a better way. It turns out that within a matter of less than 15 minutes, the liver converts aspirin to another substance called salicylic acid. So the researchers reasoned that the effects of aspirin might be from salicylic acid instead of from aspirin itself. So to test for that, they repeated the same experiments using salicylic acid instead of aspirin. And guess what? The results were the same! The salicylic acid did just as well as the aspirin. And salicylic acid does not have the side effect baggage that aspirin has. So how can we take advantage of this new information? It’s quite easy.

            Willow bark is an herb that contains the substance salicin. And when we eat willow bark, our livers convert the salicin to salicylic acid. So by taking willow bark, it is possible to get the same mitochondrial-stimulating effects that come from aspirin.“ Dr. Frank Shallenberger

            Abbreviated name Botanical name Plant part used

            PE4 Cimicifuga racemosa Root and rhizome Black cohosh

            PE5 Valeriana officinalis L. Root Valerian

            PE6 Passiflora incarnate L. Whole plant passion flower

            PE8 Ginkgo biloba Leaf Ginkgo biloba

            PE12 Apium graveolens L. Seed wild celery

            PE21 Salix alba Bark white willow

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              Thx!

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              Looks like I found it, there’s 2 papers about this research:

              http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=7665&path%5B%5D=22203

              http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=10689&path%5B%5D=33840

              All sources are “Idunn Technologies”

              PE4, PE5, PE6, PE8, PE12 and PE21 slow yeast aging:
              Abbreviated name        Botanical name              Plant part used
               PE4                    Cimicifuga racemosa         Root and rhizome
               PE5                    Valeriana officinalis L.    Root    
               PE6                    Passiflora incarnate L.     Whole plant
               PE8                    Ginkgo biloba               Leaf        
               PE12                   Apium graveolens L.         Seed    
               PE21                   Salix alba                  Bark
              
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                Thx!

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                Rather useless article… From the website it seems the referenced research is still unpublished. The only published work this team seems to have so far is this:

                Longevity extension by phytochemicals. Leonov A, Arlia-Ciommo A, Piano A, Svistkova V, Lutchman V, Medkour Y, Titorenko VI. Molecules. 2015 Apr 13;20(4):6544-72. Review. http://www.ncbi.nlm.nih.gov/pubmed/25871373

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                  Dose conversion considering body surface area leads to human “dose” of daily cacao at 3.9mg/kg for humans =)

                  hmmm… 320mg cacao powder for me daily, easy enough