From the publication:

Evidence has demonstrated that 14 days of BFR [blood flow restriction] are more effective than isometric exercise to prevent muscle waste and weakness induced by immobilization and unloading. [repeated blood flow restriction without training vs isometric training vs no intervention]

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Several randomized controlled trials and meta‐analyses have shown that RT [resistance training] with BFR (RT‐BFR) [usually low intensity, between 20% and 40% of the 1‐RM load] produces similar muscle hypertrophy response to high intensity RT, in different populations.

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Moderate to high intensity ET [endurance training] promotes significant increases in cardiorespiratory capacity, with no or small improvements in muscle strength and hypertrophy. However, when ET [endurance training] is performed with BFR (ET‐BFR), there is a significant increase in aerobic power (i.e. maximum oxygen consumption VO2max), as well as increases in muscle strength and hypertrophy.

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BFR approach has been applied to >12 000 people in Japan across different physical conditions, such as cerebrovascular, orthopaedic, cardiac, respiratory, and neuromuscular diseases, as well as obesity, diabetes, and hypertension, with no significant side effects reported on rheological response. From 300 000 training sessions, only 0.055% of practitioners developed venous thrombus, 0.008% developed pulmonary embolism, and 0.008% of the cohort presented rhabdomyolysis.