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But now there is even more excitement in terms of BDNF. A novel nutritional supplement, whole coffee fruit concentrate, has recently been shown to have a dramatic effect, in humans, in terms of raising BDNF. In a recent report in Food and Nutrition Sciences, researchers demonstrated how whole coffee fruit concentrate (WCFC) affected BDNF levels in humans. The study involved 20 young adults (25-35 years) who were asked to consume whole coffee fruit concentrate powder followed by blood evaluations of their BDNF levels. Remarkably, BDNF levels actually doubled in those individuals taking the whole coffee fruit concentrate in comparison to those who were given coffee or a placebo. - See more at: http://www.drperlmutter.com/coffee-fruit-concentrate-and-brain-cells/#sthash.g9l4Ss72.dpuf