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Major points from the publication:

  • First paper biomarking expression of the MFSD2a protein in whole human blood and serum.
  • MFSD2a levels in maternal blood on the third trimester were inversely correlated to DHA in maternal serum lyso-PL. (More DHA lyso-PL; more MSFD2a)
  • MFSD2a protein expression in maternal blood was significantly lower in gestational diabetes groups and correlated with placental MFSD2a and Z-score neonatal head circumference during the first 6 months of life. (More maternal MFSd2a; greater head circumference)
  • Infant head circumference is directly related to brain volume.
  • Gestational diabetes reduced materno-fetal DHA transport.
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